Trauma and its consequences
in old age
Topic leader: Sjacko Sobczak
Please contact the topic leader if you would like to initiate new projects or have other ideas about global collaboration related to this topic. You can also directly submit your project proposal here.
ON TRAumatiC stress and ageing: a global networK (ON TRACK)
Project group
PI: Sjacko Sobczak
Department of Neuropsychology and Psychopharmacology, Faculty of Psychology and Neuroscience; School for Mental Health and Neuroscience, Faculty of Health, Medicine and Life Sciences, Maastricht University, Maastricht, the Netherlands
E-mail: Sjacko.sobczak@maastrichtuniversity.nl
Collaborators are Welcome (CAW)!
We are looking for expert volunteers with expertise in trauma and ageing in particular from underrepresented areas (non-Western) to join us.
Current network members
Marco Boks, Universitair Medisch Centrum Utrecht, The Netherlands
Margherita Boltri, Sigmund Freud University, Milano, Italy
Liam Borelli-Millott, University of Melbourne, Australia
Erine Brocker, Stellenbosch University, South Africa
Lisa Brown, Palo Alto University, Florida USA
Monica Cations, Flinders University, Australia
Estelle Coeur, University Cote d’Azur, France
Joan Cook, Yale University, USA
Xavier Corveleyn, University Cote d’Azur, France
Gea van Dijk, NHL Stenden, The Netherlands
Ashley Dorame, Boston University, USA
Yinfei Duan, University of Alberta, Edmonton, Canada
Stéfanie Fréel, Amsterdam University Medical Centers, Amsterdam, The Netherlands
Barbara Forresi, Sigmund Freud University, Milano, Italy
Vaitsa Giannouli, Hellenic Open University, Greece
Ellen Gielkens, Mondriaan, The Netherlands
Mia Maria Günak, LMU Munich, Germany & UCL, Great Britain
Demi Havermans, Maastricht University, The Netherlands
Chris Hoeboer, Amsterdam University Medical Centers, The Netherlands
Bea Hollander-Goldfein, Transcending Trauma Project Philadelphia, USA
Tiffeny James, University of Greenwich, UK
Oj Jianqing, Singapore Institute of Technology (SIT), Singapore
Argyroula Kalaitzaki, Hellenic Mediterranean University, Heraklion, Greece
Karen Lawrence, University of Kentucky, USA
Lewina Lee, Boston University School of Medicine, USA
Andreas Maercker, University of Zurich, Switzerland
Sofia Marcolini, University Medical Center Groningen, The Netherlands
Julian MCKoy Davis, The University of the West Indies, Jamaica
Miranda Olff, Amsterdam University Medical Centers & ARQ National Psychotrauma Centre, Amsterdam, The Netherlands
Isadora Olive, UCL, Great Britain
Vasiliki Orgeta, UCL, Great Britain
Robert Pietrzak, Yale University, USA
Anica Pless Kaiser, National Center for PTSD , Boston, USA
Conny Quaedflieg, Maastricht University, The Netherlands
Alyssa Reiner, University of Pennsylvania, USA
Jessica Ruisch, Maastricht University, The Netherlands
Julia Schellong, Universität Dresden, Germany
Marjus Sela, Flinders University, Australia
Vanessa Simiola, Center for Integrated Health Care Research, Hawaii, USA
Sjacko Sobczak, Maastricht University, The Netherlands
Steven Thorp, Alliant International University, USA
Jelte Woudsma, UNO-UMCG, The Netherlands
Sedigheh Zabihi, UCL, Great Britain
Background
The global population is growing older and ageism takes place. Consequently, the number of people with dementia will also increase and is expected to double to 74.7 million by 2030 and more than triple by 2050. Several prospective studies have reported that the lifetime risks of dementia varied from 14.3% to 50% in different populations. The global costs of ageism and dementia are enormous and may be seen as a public health and social care priority worldwide.
Older adults and people with dementia may have a different symptom presentation of PTSD compared to adults. The prevalence of PTSD in these subgroups is estimated at respectively 3% and 4.7-7.8%. Possibly these are underestimations as older adults with PTSD may show a different and/ or blunted symptoms which may interfere with the clinical diagnostic process, in particular as cognitive dysfunctions are present.
The more as this last stage of life is in general a phase which is accompanied by loss experiences and feelings of impotence. All which may uncover traumatic memories and associated feelings and hence elicit (late-onset) PTSD.
Besides, PTSD has been associated with accelerated ageing and increased risk for dementia. But the long-term impact of traumatic stress on cognition and mental health in the ageing population and its determinants are insufficiently clear. Worldwide there are no collaborations of researchers who can advise clinical, social and health care policies.
Global collaborations between researchers in this area will strengthen and accelerate research on traumatic stress and its impact on ageing. An established network will aid in exchanging experience and knowledge. Consequently, efforts in this research field may be shared which will give a solid input to knowledge which is urgently needed in the current mondial ageing population. The ultimate goal is to improve prognoses for PTSD in older adults in general but also in those who are cognitive compromised such as in dementia. Proven and innovative prevention and treatment strategies can be evaluated in different settings in the care chain.
To improve global collaboration on this current topic, the Global Collaboration of Traumatic Stress is establishing a worldwide network of researchers in the field of traumatic stress, older adults and cognition.
Aims
The aim of ON TRACK network is to connect researchers worldwide who are working in the area of (mental) health care for older adults, care homes or who do research in the field of cognition (and its course) in relation to traumatic stress. Researchers who are active or interested in life-span research on the impact of traumatic stress are also invited. We want to share expertise, knowledge and experience and encourage future collaborations. Ultimately our aim of the network is to improve: i) knowledge on the impact of traumatic stress on ageing and neurodegeneration, ii) mental health prognosis for PTSD subjects over the whole life course.
Regular ON TRACK network meetings are taking place Further plans and projects are being developed.
Contact
Would you like to participate the ON TRACK network? Or do you have additional questions? Please contact: Sjacko Sobczak
ON TRACK Position paper
Project group
PI : Sjacko Sobczak and ON TRACK network members
Background
Several decades of research has shown that traumatic stress is associated with negative effects on the physical and mental health of older adults. Posttraumatic stress disorder (PTSD) is prevalent in older people, it accelerates the aging process and has been found to increase dementia risk. Despite the health and social care burden of living with trauma and PTSD in late life, including on older adults’ daily functioning and quality of life, systematic research into the prevalence, prognosis, and treatments for trauma and PTSD in older adults, as well as the mechanisms underlying trauma and ageing, remains limited.
Aims
The aim of the position paper is to strengthen and accelerate research on traumatic stress and ageing with efforts to improve prognosis and quality of life for older people affected by traumatic stress and PTSD. Increasing our knowledge on assessment and treatment will also improve recognition of PTSD and the development and evaluation of evidence-based treatments that will improve patient outcomes. Increasing knowledge on trauma and ageing mechanisms can further foster the development of more targeted and effective prevention programs. Specifically, this paper seeks to derive and report on evidence-based knowledge related to four domains: ageing mechanisms underlying trauma and ageing, progress in assessment and prevalence, and developments in care. The paper will also identify a specific call to action for future directions in research, clinical practice, and policy.
Status: Completed
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Sobczak, S., Orgeta, V., Beenakker, M., Boks, M., Boltri, M., Cations, M., Coeur, E., Cook, J. M., Corveleyn, X., Dorame, A.-N., van Dijk, G. C., Forresi, B., Fréel, S., Gómez-Bautista, D., Günak, M. M., Havermans, D. C. D., Hopwood, M., O, J., Lawrence, K. A., Lee L.O., Maercker, A., Marsman, A., Olivé, I., Quaedflieg, C.W.E.M., Ruisch, J., Thorp, S.R., Woudsma, J.S., Zabihi, S,. Olff, M. and Global Collaboration on Traumatic Stress. (2025). Post-traumatic stress disorder in older adults: A global collaboration on setting the future research agenda. The Lancet. Healthy Longevity, 6(6), 100720. https://doi.org/10.1016/j.lanhl.2025.100720
The lifetime prevalence and incidence of trauma exposure and PTSD among older adults: a systematic review
Project group
Monica Cations (Australia) (PI), Vasiliki Orgeta (UK), Sjacko Sobczak (Netherlands), Jean Stafford (UK), Marjus Sela (UK), Jelte Woudsma (Netherlands), Miranda Olff (Netherlands), Joan Cook (USA)
Background
Despite the significant impact of trauma on older adults’ physical and mental health estimates of the prevalence of lifetime trauma exposure among older adults remain poorly understood, with variation across studies.
Aims
The aim of this systematic review is to generate global estimates of the lifetime prevalence and incidence of exposure to psychologically traumatic events, lifetime PTSD, and current PTSD among adults aged 60 years and older.
KOMPAS-study
Trauma, Dementia, and Trauma‑Sensitive Care: Invitation for International Research Collaboration
Project group:
Sjacko Sobczak (Netherlands), Gea van Dijk (Netherlands), Demi Havermans (Netherlands), Jessica Vervoort (Netherlands), Janet Been-Dahmen (Netherlands), Linda Akkermans-Smithuis (Netherlands)
Background
Emerging evidence from our TRADE research programme indicates that up to 90% of people with dementia in long-term care have a history of psychological trauma, which—combined with cognitive decline—may trigger re-experiencing and severe behavioural symptoms. These insights highlight an urgent need for trauma‑sensitive care approaches tailored to the psychogeriatric context. Through previous projects such as TRADE, TRACE, TraumaTestament, and GLISTEN, we have developed substantive knowledge on trauma in dementia, its impact on care teams, and the requirements for trauma-informed practice.
Our current implementation project translates this expertise into practical, scalable knowledge products, including training modules for care teams and psychoeducational materials for family members. Using co-creation methodologies and established implementation science frameworks, we work closely with long-term care organisations to embed trauma-informed care sustainably within psychogeriatric wards. National partners support broader dissemination and adaptation of these tools.
Aims
The project aims to enhance professional competence, reduce care burden, strengthen collaboration with families, and ultimately improve the quality of life of people with dementia who are affected by trauma. Diversity, ethical challenges, and lived experience perspectives are integral to the programme.
We welcome collaboration with international researchers interested in trauma, dementia, implementation science, in neuropsychiatric care. Opportunities include joint studies, methodological exchange, cross‑cultural comparison, and further development of trauma‑sensitive care frameworks.
Collaborators are Welcome (CAW)!
If you are interested in partnering with us, we would be delighted to connect: Sjacko Sobczak

TRAuma and DEmentia (TRADE)
Project group
PI: Sjacko Sobczak
Department of Neuropsychology and Psychopharmacology, Faculty of Psychology and Neuroscience; School for Mental Health and Neuroscience, Faculty of Health, Medicine and Life Sciences, Maastricht University, Maastricht, the Netherlands
E-mail: Sjacko.sobczak@maastrichtuniversity.nl
Background
Studies on the comorbidity of PTSD in dementia are sparse, probably, because of the lack of a valid diagnostic tool. As subjects with dementia are often unable to give a valid report of their life history, in particular a delayed-onset PTSD may be easily missed. It is estimated that the comorbidity of PTSD in dementia is between 4.7- 7.8%.
Mondial the number of people with dementia are estimated at about 35.6 million in 2010 which is about to double every 20 years till approximately 115.4 million in 2050. Based on the suggested comorbidity rate of PTSD, number of affected subjects is substantial and will increase steadily in the coming years.
PTSD and dementia are both known for their impact on the quality of life of those affected. In clinical practice, we see that the combination of both causes significant psychological suffering. And that while it is precisely in people with dementia that the experiences of these violent events often revive. People with dementia and PTSD may live in constant fear and apprehension, and may be trapped in the re-experience of heavy events which may be paired with screaming and aggression. As the diagnosis of PTSD may be easily missed these neuropsychiatric symptoms are often described as ‘unexplained’ or ‘problem’ behavior. Effective proven treatment advices are missing.
The forthcoming global ageing population and related spate of dementia will urge us to improve care for these people.
Aims
The TRADE-project proposes to improve knowledge and clinical care for subjects suffering from both dementia and PTSD. Aims of the project include:
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Develop a valid diagnostic tool to diagnose PTSD and its severity in dementia subjects.
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Investigate the comorbidity rate of PTSD in dementia subjects living in clinical settings and care homes.
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Investigate the aimed population with respect to: neuropsychiatric symptoms and related behavioral problems, frailty and physical stress parameters, quality of life and health care burden and epigenetic profiles.
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Investigate the effects on these parameters of EMDR-treatment.
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Providing information and evidence to inform the development of policy and services for care of subjects with dementia and PTSD.
Treatments for post-traumatic stress disorder in older adults: a systematic review of the evidence
Project group
Vasiliki Orgeta (UK) (PI), Sedigheh Zabihi (UK), Sjacko Sobczak (Netherlands), Joan Cook (USA), Ellen Gielkens (Netherlands), Miranda Olff (Netherlands), Conny Quaedflieg (Netherlands)
Background
Despite evidence that over 70% of older people are exposed to a potentially traumatic event during their lifetime, and reports that post-traumatic stress disorder (PTSD) affects over 7% of the population of older people, research in the clinical effectiveness of both pharmacological and non-pharmacological interventions such as psychological treatments, in treating PTSD symptoms continues to be limited.
Aims
The aim of the present review therefore is to examine the clinical-effectiveness of both pharmacological (i.e., venlafaxine, selective serotonin reuptake inhibitors) and non-pharmacological trauma-focused and non-trauma focused treatments (trauma-focused CBT, CBT, cognitive processing therapy, eye movement desensitisation and reprocessing), in reducing PTSD-related symptoms in older people. A secondary aim is to assess the quality of evidence and make recommendations for clinical guidelines worldwide.
Status: completed
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Gómez-Bautista, D., Lye, V., Zabihi, S., Beenakker, M., Günak, M. M., Roche, M., Sobczak, S., Cook, J. M., Cations, M., Olff, M., & Orgeta, V. (2025). Effectiveness of treatments for post-traumatic stress disorder for older people: A systematic review and meta-analysis of randomized controlled trials. Journal of Affective Disorders, 120433. https://doi.org/10.1016/j.jad.2025.120433
The diagnostic accuracy of trauma and PTSD assessment in older adults: a systematic review
Project group
Karen Lawrence (USA), Demi Havermans (Netherlands), Estelle Coeur (France), O Jiaqing (Singapore), Joan Cook (USA), Sjacko Sobczak (Netherlands), Miranda Olff (Netherlands)
Background
While many assessment instruments are available for diagnosing PTSD in the general population, it is unclear which measures have strong psychometric properties (or are reliable and valid) among older adults. In order to enhance knowledge and accurate identification of PTSD in older adults, it is important to determine which instruments are available and have been validated in this population.
Aims
This systematic review aims to assess the diagnostic accuracy with respect to sensitivity and specificity of assessing trauma and PTSD among adults 60 years and older
Status: completed
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Havermans, D. C. D., Coeur, E. M. N., Jiaqing, O., Rippey, C. S., Cook, J. M., Olff, M., Hoeboer, C., Sobczak, S., & Lawrence, K. A. (2025). The diagnostic accuracy of PTSD assessment instruments used in older adults: A systematic review. European Journal of Psychotraumatology, 16(1), 2498191. https://doi.org/10.1080/20008066.2025.2498191
TICTool
Co-designing a Trauma Informed Care (TIC) tool in dementia care settings: a Delphi study
Project group
Jelte Woudsma (Netherlands), Gea van Dijk (Netherlands), Sjacko Sobczak (Netherlands), Jessica Vervoort (Netherlands), Milou Molkenboer (Netherlands), Monica Cations (Australia), Care Beard (Netherlands)
Background
Research demonstrates that post-traumatic stress disorder (PTSD) symptoms frequently surface or (re-)emerge in dementia patients, especially in care settings where individuals lose independence, autonomy, loss of control, face restricted choices, or encounter unfamiliar environments. Since individuals with dementia often cannot verbalize their distress, caregivers need to recognize environmental and interpersonal cues that may reactivate past trauma in order to provide compassionate, person-centered care.
Aims
This Delphi study aims to co-design a trauma informed care (TIC) tool including an user manual with experts in the field.
The trauma-informed care tool will be designed to be used as a behavioral counseling intervention in dementia care. It is proposed that this tool be a single page and is easily applied to recognize environmental and interpersonal cues. The user manual will be developed with the goal to explain the need for trauma-informed knowledge, and the evidence that sits behind the tool which can be used in clinical practice. Together, the trauma-informed care tool and manual will support clinicians and professionals in identifying and responding to trauma-related needs in people with dementia.
Status: starting up
Collaborators are Welcome (CAW)!
****EXPERTS NEEDED****
We are looking for clinicians and healthcare experts with:
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Recognized expertise in the topic area of dementia, trauma, or trauma-informed dementia care, demonstrated through a professional role, research, or publications;
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Related experience in clinical, academic, policy, or service delivery roles.
If you are interested or want more information, please contact us: jelte.woudsma@nb.nl
References / Output
Driessen, S., Ponds, R., van Alphen, B., Nederstigt A., Deckers, K. & Sobczak, S. (2023). Treating Symptoms of Posttraumatic Stress in People with Dementia: Expert Consensus Using the Delphi Method. Clinical Gerontologist. DOI: 10.1080/07317115.2023.2170842
Gómez-Bautista, D., Lye, V., Zabihi, S., Beenakker, M., Günak, M. M., Roche, M., Sobczak, S., Cook, J. M., Cations, M., Olff, M., & Orgeta, V. (2025). Effectiveness of treatments for post-traumatic stress disorder for older people: A systematic review and meta-analysis of randomized controlled trials. Journal of Affective Disorders, 120433. https://doi.org/10.1016/j.jad.2025.120433
Guo, J., Orgeta, V., Olivé, I., Hoff, E., Huntley, J., Olff, M., & Sobczak, S. (2024). Biomarkers associated with cognitive impairment in post-traumatic stress disorder: A systematic review of current evidence. Ageing Research Reviews, 102198. https://doi.org/10.1016/j.arr.2024.102198
Havermans, D. C. D., Coeur, E. M. N., Jiaqing, O., Rippey, C. S., Cook, J. M., Olff, M., Hoeboer, C., Sobczak, S., & Lawrence, K. A. (2025). The diagnostic accuracy of PTSD assessment instruments used in older adults: A systematic review. European Journal of Psychotraumatology, 16(1), 2498191. https://doi.org/10.1080/20008066.2025.2498191
Havermans, D. C., van Alphen, S. P., Olff, M., Van der Velden-Daamen, M., Verhey, F., Rutten, B. P., ... & Sobczak, S. (2022). The need for a diagnostic instrument to assess post-traumatic stress disorder in people with dementia: findings from a Delphi study. Journal of geriatric psychiatry and neurology, 08919887221103583. https://doi.org/10.1177/08919887221103583
National Center for PTSD. (2019). PTSD and Aging. PTSD Research Quarterly, No. 4. Retrieved from https://www.ptsd.va.gov/publications/rq_docs/V30N4.pdf
Sobczak, S., Olff, M., Rutten, B.P.F., Verhey, F., Deckers, K.. (2021). Comorbidity rates of posttraumatic stress disorder in dementia. European Journal of Psychotraumatology. 12 (1): 1-10. DOI: 10.1080/20008198.2021.1883923
Sobczak, S., Orgeta, V., Beenakker, M., Boks, M., Boltri, M., Cations, M., Coeur, E., Cook, J. M., Corveleyn, X., Dorame, A.-N., van Dijk, G. C., Forresi, B., Fréel, S., Gómez-Bautista, D., Günak, M. M., Havermans, D. C. D., Hopwood, M., O, J., Lawrence, K. A., Lee L.O., Maercker, A., Marsman, A., Olivé, I., Quaedflieg, C.W.E.M., Ruisch, J., Thorp, S.R., Woudsma, J.S., Zabihi, S,. Olff, M. and Global Collaboration on Traumatic Stress. (2025). Post-traumatic stress disorder in older adults: A global collaboration on setting the future research agenda. The Lancet. Healthy Longevity, 6(6), 100720. https://doi.org/10.1016/j.lanhl.2025.100720
Sobczak, S., van Kordenoordt, M., Uiterwijk, R., Cook, J. M., Havermans, D. C. D., Vossen, L., Ramakers, I., Olff, M., & van Alphen, S. P. J. (2024). Challenges in diagnosing Posttraumatic stress disorder in dementia: A case report. Psychiatry Research Case Reports, 3(1), 100207. https://doi.org/10.1016/j.psycr.2024.100207
van Dongen, D. H., Havermans, D., Deckers, K., Olff, M., Verhey, F., & Sobczak, S. (2022). A first insight into the clinical manifestation of posttraumatic stress disorder in dementia: a systematic literature review. Psychogeriatrics. https://doi.org/10.1111/psyg.12830

